Robert M Graham

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Robert M Graham
Born(1948-04-02)2 April 1948
Sydney, Australia
  • Australian
  • American
Alma materUniversity of New South Wales
Known forContributions to adrenergic receptor structure, function and signalling
  • Foreign Member
  • Royal Danish Academy of Sciences and Letters (2010)
Scientific career
  • Molecular Cardiology
  • Molecular Pharmacology
  • Victor Chang Cardiac Research Institute
  • University of New South Wales
  • University of Texas Southwestern Medical School
  • Harvard Medical School
  • Cleveland Clinic Foundation
ThesisMolecular characterization of the α1-adrenergic receptor (1988)
WebsiteProfessor Bob Graham

Robert “Bob” Michael Graham AO, Australian Academy of Science, FAHMS (born 1948) is an Australian-born clinician-scientist; the Des Renford Professor of Medicine at University of New South Wales[1]; and the Head of the Molecular Cardiology and Biophysics Division at Victor Chang Cardiac Research Institute[2].


Robert Graham received his medical training, MBBS with Honours, and his MD degree from the University of New South Wales. He then trained as a physician in internal medicine and cardiorenal disease in Australia and the US, leading to Fellowships of the Royal Australian College of Physicians and the American College of Physicians.

In the US he received postdoctoral training in pharmacology (Alfred G. Gilman, Chairman and Nobel Laureate) and medicine (Don Seldin, Chairman) at the University of Texas Southwestern Medical School. Graham was then appointed as an Assistant Professor in Pharmacology and Medicine at University of Texas Southwestern Medical School.[3]


In 1982, Graham moved to the Massachusetts General Hospital (Cellular and Molecular Research Laboratory, Edgar Haber, Chairman) and Harvard Medical School, Boston as an Associate Professor of Medicine. During his time in Boston, he did a sabbatical in the laboratory of Nobel Laureate H. Gobind Khorana at the Massachusetts Institute of Technology. In 1989, he moved to the Cleveland Clinic Foundation as the Robert C. Tarazi Chairman of the Molecular Cardiology Department, and Professor of Physiology and Biophysics at Case Western Reserve University School of Medicine, Cleveland, Ohio.[3]

Graham returned to Australia in 1994 as the inaugural Executive Director at the Victor Chang Cardiac Research Institute[4] - a position he held until stepping down in March 2020[5].


Graham's research is reported in over 290 peer-reviewed papers[6] and cited over over 26,000 times[7].

For many years his research has focused on molecular cardiology, with emphasis on circulatory control mechanisms, receptor signalling, hypertension and cardiac hypertrophy. Together with his colleague Dr Charles Homcy, his work contributed to our understanding of receptor structure, function and signalling. This work subsequently led to the discovery that a protein crosslinking enzyme also functions as a unique multifunctional protein involved in receptor signalling.

More recently, together with colleagues, Dr Ahsan Husain and Dr Siiri Iismaa, Graham has been actively involved in studies of cardiac regeneration and the application of stem cells for the treatment of heart diseases, and with A/Prof Eleni Giannoulatou, the pathophysiology and genetics of spontaneous coronary artery dissection.

In 2021, with Professor Glenn King and Dr Nathan Palpant, he co-founded Infensa Bioscience, an Australian biotechnology company.

He serves on the Board of Directors of the Lowy Medical Research Institute[8][9] in California; and Impedimed[10][11], a Brisbane-based medical device company.

Awards and recognition

In 1982, he was recognised as an Established Investigator by the American Heart Association.

In 1994, he received the Eccles Award from the National Health & Medical Research Council, Australia.

In 1998, Graham was named an Outstanding Graduate at the University of New South Wales Medical School.

In 2001, Graham received the RT Hall Prize from the Cardiac Society of Australia and New Zealand and made a Fellow of the American Heart Association (FAHA).

In 2002, Graham was made a Fellow of the Australian Academy of Science (FAA).

In 2003, Graham was awarded the Centenary of Federation Medal by the Federal Government of Australia[12].

In 2006, Graham was made a Fellow of the Cardiac Society of Australia and New Zealand (FCSANZ).

In 2008, Graham received a Lifetime Achievement Award from the National Heart Foundation of Australia.

In 2009, Graham was awarded an Order of Australia (AO)[13] and voted President of the Association of Australian Medical Research Institutes[14].

In 2010, Graham was made a Foreign Member of The Royal Danish Academy of Sciences and Letters[15] in the Natural Sciences Class.

In 2011, Graham was made a Life Member of the NSW Division of the Heart Foundation of Australia[16].

In 2014, Graham was named a Foundation Fellow of the Australian Academy of Health and Medical Sciences (FAHMS)[17]

In 2015, Graham was a Founding Director of the Australian Cardiovascular Alliance[18].

In 2016, Graham received a NSW Ministerial Award for Cardiovascular Research Excellence[19].

In 2018, Graham was made a Life Member of the Royal Australasian College of Physicians.


  1. "The heart that regenerates itself". UNSW Medicine - St Vincent's Clinical School.{{cite web}}: CS1 maint: url-status (link)
  2. "Molecular Cardiology Laboratory - Victor Chang Institute". The Victor Chang Cardiac Research Institute. Retrieved 2021-09-09.
  3. 3.0 3.1 "Professor Bob Graham | Victor Chang Cardiac Research Institute". The Victor Chang Cardiac Research Institute. Retrieved 2021-09-09.
  4. "How billionaires, surgeons and royals built the Victor Chang institute". Australian Financial Review. 2019-11-15. Retrieved 2021-09-09.
  5. Professor Bob Graham steps down after 25 years at Victor Chang Cardiac Research Institute, Australian Broadcasting Corporation, 2019-11-19, retrieved 2021-09-09
  6. "Select Publications by Professor Robert M Graham". UNSW Sydney.{{cite web}}: CS1 maint: url-status (link)
  7. "Robert M Graham". Google Scholar.{{cite web}}: CS1 maint: url-status (link)
  8. "Lowy Medical Research Institute Limited" (PDF). Treasury.{{cite web}}: CS1 maint: url-status (link)
  9. "Robert Graham, AO, FAA, MD". The Lowy Medical Research Institute. 2015-11-24. Retrieved 2021-09-09.
  10. "ImpediMed announces changes to Board of Directors".{{cite web}}: CS1 maint: url-status (link)
  11. "Robert M. Graham, AO, FAA, FAHMS, MBBS, MD, FRACP, FACP, FAHA | ImpediMed". Retrieved 2021-09-09.
  12. "Centenary Medals for 15,464". The Sydney Morning Herald. 2003-04-25. Retrieved 2021-09-09.
  13. "AUSTRALIAN HONOURS SEARCH FACILITY". Retrieved 2021-09-09.{{cite web}}: CS1 maint: url-status (link)
  14. "Campaign to merge MRIs under fire". AAMRI. 2009-12-02. Retrieved 2021-09-09.
  15. "Royal Academy". Retrieved 2021-09-09.
  16. "Annual Report 2016" (PDF). The Heart Foundation - New South Wales.{{cite web}}: CS1 maint: url-status (link)
  17. "Fellowship of the Australian Academy of Health and Medical Sciences October 2016" (PDF). Fellowship of the Australian Academy of Health and Medical Sciences.{{cite web}}: CS1 maint: url-status (link)
  18. "Directors & Executive | Australian Cardiovascular Alliance (ACvA) - Australian Cardiovascular Alliance (ACvA)". Retrieved 2021-09-09.
  19. "Annual Review 2016" (PDF). Heart Foundation.{{cite web}}: CS1 maint: url-status (link)

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