Mohammad Imran Siddiqi
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Mohammad Imran Siddiqi | |
|---|---|
| Born | 30 March 1971 Aligarh, Uttar Pradesh, India |
| Nationality | Indian |
| Alma mater | All India Institute of Medical Sciences (AIIMS), New Delhi |
| Scientific career | |
| Fields | Biophysics, Bioinformatics |
| Institutions | CSIR-Central Drug Research Institute |
| Website | cdri |
Mohammad Imran Siddiqi is an Indian bioinformatician and scientist, currently serving as Chief Scientist:[1] at the CSIR-Central Drug Research Institute (CDRI) in Lucknow, India. He is known for his contributions to cancer biology, molecular medicine, computational biology, Computational Drug Designing, Computational Biophysics, Cheminformatics and Computational Chemistry, and drug discovery.
He is a Group Leader at the Centre for Computational Biology and Bioinformatics (CBB) at CDRI and heads a research group focused on integrating computational and experimental approaches to biomedical research. He also serves as a Professor at the Academy of Scientific & Innovative Research (AcSIR).[2] [3]
Education
Dr. Siddiqi completed his postgraduate and doctoral studies in Biophysics at the All India Institute of Medical Sciences (AIIMS), New Delhi. He earned his Master of Science (M.Sc.) in Biophysics in 1995, followed by a Doctor of Philosophy (Ph.D.) in Biophysics in 2001.
Career
Dr. Mohammad Imran Siddiqi is a Chief Scientist at the CSIR–Central Drug Research Institute (CDRI), Lucknow, India. His career spans interdisciplinary research in bioinformatics, cancer biology, molecular medicine, and computational drug discovery.
Following the completion of his doctoral research in biophysics at the All India Institute of Medical Sciences (AIIMS), New Delhi, Dr. Siddiqi undertook several international postdoctoral research appointments. From 2000 to 2003, he was a Postdoctoral Fellow supported by the Federal Ministry of Education and Research (BMBF), Germany, where he contributed to research at the interface of computational and molecular sciences. He subsequently held a Visiting Postdoctoral Fellowship awarded by the Natural Sciences and Engineering Research Council of Canada (NSERC) during 2003–2004.
At CDRI, Dr. Siddiqi is a Group Leader at the Centre for Computational Biology and Bioinformatics (CBB), where he heads a research group focused on applying computational and systems biology approaches to biomedical problems. His work integrates bioinformatics, molecular modeling, and experimental validation to support drug discovery and translational research.
In addition to his research leadership at CDRI, Dr. Siddiqi serves as a Professor at the Academy of Scientific & Innovative Research (AcSIR), where he is involved in graduate teaching and doctoral supervision in life sciences and bioinformatics.
Dr. Siddiqi has also participated in international scientific collaborations and knowledge-exchange initiatives. He has received travel and subsistence awards from the International Centre for Theoretical Physics (ICTP) and the International Centre for Science and High Technology (ICS-UNIDO) to participate in and contribute to international conferences on drug development and drug design for developing countries. In 2008, he was invited by ICS-UNIDO to serve as an International Consultant for a research program focused on the development of anti-tubercular agents.
Awards and honors
Dr. Siddiqi has received several national and international fellowships and honors in recognition of his contributions to scientific research[4]
- Natural Sciences and Engineering Research Council of Canada (NSERC) – Visiting Postdoctoral Fellowship, Government of Canada (2003–2004).
- Federal Ministry of Education and Research (BMBF), Germany – Postdoctoral Research Fellowship (2000–2003).
- International Centre for Theoretical Physics (ICTP), Trieste, Italy – Travel and Subsistence Award for participation in the Conference on Drug Development for the Third World (June 5–9, 2006).
- International Centre for Science and High Technology (ICS-UNIDO), Trieste, Italy – Travel and Subsistence Award for delivering an invited talk at the International Conference on Drug Design and Discovery for Developing Countries (July 3–5, 2008).
- International Centre for Science and High Technology (ICS-UNIDO), United Nations Industrial Development Organization – Invited International Consultant for a research program on the development of anti-tubercular agents (September 20, 2008 – November 19, 2008).
Major Research Work
Dr. Mohammad Imran Siddiqi has authored and co-authored more than 250 research papers[5] published in peer-reviewed national and international scientific journals. Among Dr. Mohammad Imran Siddiqi’s notable research[6] contributions is the study titled “A peptide inhibitor of HIV-1 protease using alpha, beta-dehydro residues: a structure-based computer model.”[7] In this work, he employed structure-based computational modeling to design a peptide inhibitor targeting the HIV-1 protease, a key enzyme required for viral maturation and replication. The research demonstrated how the incorporation of α,β-dehydro amino acid residues could enhance conformational stability and binding specificity of peptide inhibitors. This study contributed to early efforts in computer-aided drug design, highlighting the potential of rational, structure-guided approaches in developing antiviral therapeutics.
References
- ↑ "Chief Scientist at CSIR-Central Drug Research Institute". CSIR-Central Drug Research Institute.
{{cite web}}: CS1 maint: url-status (link) - ↑ "CSIR-CDRI Lucknow".
- ↑ "Faculty of AcSIR | AcSIR - Academy of Scientific & Innovative Research".
- ↑ "Fellowship and Honor".
{{cite web}}: CS1 maint: url-status (link) - ↑ "Google Scholar".
{{cite web}}: CS1 maint: url-status (link) - ↑ "Notable Research Work".
{{cite web}}: CS1 maint: url-status (link) - ↑ "A peptide inhibitor of HIV-1 protease using alpha, beta- dehydro residues: a structure based computer model". Indian Journal of Biochemistry & Biophysics. 38 (1–2): 90–95.
External links
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