Michael J. Sadowsky

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Michael J. Sadowsky
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Born (1955-01-12) January 12, 1955 (age 69)
Long Island, New York, U.S.A.
NationalityAmerican
CitizenshipUnited States of America
Education
  • Bachelor's degree in Bacteriology
  • Master's degree in Microbiology
  • PhD
Alma mater
  • University of Wisconsin- Madison
  • University of Wisconsin Oshkosh
  • University of Hawaii
OccupationMicrobiologist
Known for
  • E. coli source identification
  • Fecal microbiota transplant
Spouse(s)Suzanne
Parent(s)Nathan Sadowsky, Judith Sadowsky
Awards
  • Young Investigator Award (1990)
  • Time (magazine) Innovator (2006)
  • Distinguished McKnight Professorship (2004)

Michael J. Sadowsky is an American microbiologist at the University of Minnesota in the Twin Cities. He is a Professor in the Department of Soil, Water, and Climate[1] as well as the Director of the BioTechnology Institute[2]. His research over the past 40 years has focused on the nature of bacteria and bacterial genes in ecological settings, with a particular focus on soil bacteria that are involved in nitrogen fixation[1]. He was an early and important contributor to determining the source of E. coli in waterways[3][4] and discovering the biological mechanism underlying the medical procedure known as fecal microbiota transplant[5][6].

Early life and education

Michael was born and raised on Long Island by Nathan and Judith Sadowsky[7], and worked as an auto mechanic during his teenage years. He attended the University of Wisconsin- Madison for his Bachelor's degree in Bacteriology and the University of Wisconsin Oshkosh for his Master's degree in Microbiology[8]. After completing his PhD dissertation, Physiological, serological, and plasmid characterization of fast-growing rhizobia that nodulate soybeans[9], in the laboratory of B. Ben Bohlool at the University of Hawaii[10], he performed postdoctoral research at McGill University[11], where he met his wife Suzanne[7].

Career

Noteworthy accomplishments of Michael Sadowsky include the development of an analysis technique to distinguish between animal and human E. coli in waterways[3][4], work that was ultimately featured in Time (magazine)[12]; the discovery of the mechanisms underlying the resolution of recurrent C. difficile infection treated with fecal microbiota transplant[5][6]; the development of standardized protocols for preparing frozen samples for fecal microbiota transplant[13]; and, the discovery of a novel symbiosis mechanism between soil bacteria and legumes[14]. He also holds 10 patents for technology related to his research[8], and was the Editor of the widely used text book, The Fecal Bacteria[15]. As of June 2020 he has authored or co-authored over 400 publications, which have been cited over 25,000 times, and his h-index is 80[16].

In the media

     

References

  1. ↑ 1.0 1.1 "Michael Sadowsky". Retrieved 2020-06-16.
  2. ↑ "BioTechnology Institute- Sadowsky". Retrieved 2020-06-16.
  3. ↑ 3.0 3.1 Dombek, PE; Johnson, LK; Zimmerley, ST; Sadowsky, MJ (2000). "Use of Repetitive DNA Sequences and the PCR To Differentiate Escherichia coli Isolates from Human and Animal Sources". Applied and Environmental Microbiology. 66 (6): 2572–2577. doi:10.1128/aem.66.6.2572-2577.2000. PMID 10831440.
  4. ↑ 4.0 4.1 Hamilton, MJ; Yan, T; Sadowsky, MJ (2006). "Development of Goose- And Duck-Specific DNA Markers to Determine Sources of Escherichia Coli in Waterways". Applied and Environmental Microbiology. 72 (6): 4012–4019. doi:10.1128/AEM.02764-05. PMID 16751510.
  5. ↑ 5.0 5.1 Khoruts, A; Dicksved, J; Jansson, JK; Sadowsky, MJ (2010). "Changes in the Composition of the Human Fecal Microbiome After Bacteriotherapy for Recurrent Clostridium difficile-associated Diarrhea". Clinical Gastroenterology. 44 (5): 354–360. doi:10.1097/MCG.0b013e3181c87e02. PMID 20048681.
  6. ↑ 6.0 6.1 Sadowsky, MJ; Khoruts, A (2016). "Faecal microbiota transplantation is promising but not a panacea". Nature Microbiology. 1. doi:10.1038/nmicrobiol.2016.15. PMID 27572174.
  7. ↑ 7.0 7.1 "Judith Ann Sadowsky". Retrieved 2020-06-10.
  8. ↑ 8.0 8.1 "Curriculum Vitae" (PDF). Retrieved 2020-06-10.
  9. ↑ "Sadowsky Dissertation". Retrieved 2020-06-10.
  10. ↑ "Biological Nitrogen Fixation Bulletin, Volume X, Number 2" (PDF). Retrieved 2020-06-10.
  11. ↑ "EPA Science Advisory Board Homeland Security Advisory Committee" (PDF). Retrieved 2020-06-16. {{cite web}}: Cite has empty unknown parameter: |1= (help)
  12. ↑ "Epidemiology: Forging the Future: Keeping The Beaches Safe". Retrieved 2020-06-15.
  13. ↑ Hamilton, MJ; Weingarden, AR; Sadowsky, MJ; Khoruts, A (2012). "Standardized Frozen Preparation for Transplantation of Fecal Microbiota for Recurrent Clostridium difficile Infection". The American Journal of Gastroenterology. 107 (5): 761–767. doi:10.1038/ajg.2011.482. PMID 22290405.
  14. ↑ Giraud, E; Lionel, M; Vallenet, D; Barbe, V; Cytryn, E; Avarre, J-C; Jaubert, M; Simon, D; Cartieaux, F; Prin, Y; Bena, G; Hannibal, L; Fardoux, J; Kojadinovic, M; Vuillet, L; Lajus, A; Cruveiller, S; Rouy, Z; Mangenot, S; Segurens, B; Dossat, C; Franck, WL; Woo-Suk, C; Saunders, E; Bruce, D; Richardson, P; Normand, P; Dreyfus, B; Pignol, D; Stacey, G; Emerich, D; Vermeglio, A; Medigue, C; Sadowsky, MJ (2007). "Legumes Symbioses: Absence of Nod Genes in Photosynthetic Bradyrhizobia". Science. 316 (5829): 1307–1312. doi:10.1126/science.1139548. PMID 17540897.
  15. ↑ "The Fecal Bacteria". Retrieved 2020-06-10.
  16. ↑ "Google Scholar- Michael Sadowsky". Retrieved 2020-06-16. {{cite web}}: Cite has empty unknown parameter: |1= (help)

External links

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