Marino Zerial

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Marino Zerial (born 8 August 1958 in Trieste, Italy) is an Italian cell biologist.

Career

Marino Zerial graduated from the University of Trieste (Italy) in 1982 with a degree in biology. His thesis focused on Lysosomal storage disease. Following his graduation, he worked as a postdoctoral researcher at the Institut Jacques Monod in Paris, France and the European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany.

In 1989, he became a group leader at the EMBL, and in 1998 he became a co-founder and Max Planck Director of the Max Planck Institute of Molecular Cell Biology and Genetics (MPI-CBG) in Dresden, Germany. Additionally, he holds an honorary professorship at the Medical Faculty of Technische Universität Dresden.

In 2023 he was appointed Director of the Human Technopole Foundation, the new Italian institute for life sciences in Milan, Italy.[1] [2]

Research

Marino Zerial's research has been instrumental in advancing the understanding of the molecular mechanisms of endocytosis. His work on Rab GTPase, which are master regulators of organelle biogenesis and membrane fusion, has established key principles that are widely accepted as foundational knowledge.[3] [4] He has also worked on various translational projects, including studying the role of endocytosis in bacterial infection, developing image-based high content screenings, investigating macromolecule therapeutics, and researching human liver diseases [5] [6] [7].

Awards

  • 1994: FEBS Anniversary Prize [8]
  • 1999: Chiara D'Onofrio Prize, Italy
  • 1996: elected member of the European Molecular Biology Organization [9]
  • 2006: Gottfried Wilhelm Leibniz Prize, Germany [10]
  • 2019: member of the Istituto Veneto di Scienze, Lettere ed Arti [11]
  • 2021: elected as International Honorary Member of the American Academy of Arts and Sciences [12]

References

  1. "Chi è Marino Zerial nuovo numero 1 dello Human Technopole". startupitalia.eu. 2023-02-23. Retrieved 2023-03-02.
  2. "Marino Zerial appointed as new Human Technopole Director". Human Technopole. 2023-02-22. Retrieved 2023-03-02.
  3. Christoforidis, Savvas; McBride, Heidi M.; Burgoyne, Robert D.; Zerial, Marino. "The Rab5 effector EEA1 is a core component of endosome docking". Nature. 397 (6720): 621–625. doi:10.1038/17618. ISSN 1476-4687.
  4. Zeigerer, Anja; Gilleron, Jerome; Bogorad, Roman L.; Marsico, Giovanni; Nonaka, Hidenori; Seifert, Sarah; Epstein-Barash, Hila; Kuchimanchi, Satya; Peng, Chang Geng; Ruda, Vera M.; Conte-Zerial, Perla Del; Hengstler, Jan G.; Kalaidzidis, Yannis; Koteliansky, Victor; Zerial, Marino. "Rab5 is necessary for the biogenesis of the endolysosomal system in vivo". Nature. 485 (7399): 465–470. doi:10.1038/nature11133. ISSN 1476-4687.
  5. Morales-Navarrete, Hernán; Nonaka, Hidenori; Scholich, André; Segovia-Miranda, Fabián; de Back, Walter; Meyer, Kirstin; Bogorad, Roman L; Koteliansky, Victor; Brusch, Lutz; Kalaidzidis, Yannis; Jülicher, Frank; Friedrich, Benjamin M; Zerial, Marino (2019-06-17). Sens, Pierre; Chakraborty, Arup K; Ladoux, Benoit (eds.). "Liquid-crystal organization of liver tissue". eLife. 8: e44860. doi:10.7554/eLife.44860. ISSN 2050-084X.
  6. Belicova, Lenka; Repnik, Urska; Delpierre, Julien; Gralinska, Elzbieta; Seifert, Sarah; Valenzuela, José Ignacio; Morales-Navarrete, Hernán Andrés; Franke, Christian; Räägel, Helin; Shcherbinina, Evgeniya; Prikazchikova, Tatiana; Koteliansky, Victor; Vingron, Martin; Kalaidzidis, Yannis L.; Zatsepin, Timofei (2021-10-04). "Anisotropic expansion of hepatocyte lumina enforced by apical bulkheads". The Journal of Cell Biology. 220 (10): e202103003. doi:10.1083/jcb.202103003. ISSN 1540-8140. PMC 8329733. PMID 34328499.
  7. "How mRNA therapeutics reach cells".
  8. "FEBS Anniversary Prize der GBM - Homepage der Gesellschaft für Biochemie und Molekularbiologie e.V." gbm-online.de. Retrieved 2023-03-02.
  9. "The EMBO communities – EMBO Members – EMBO". 2020-08-20. Retrieved 2023-03-02.
  10. "Gottfried Wilhelm Leibniz-Preis 2006". www.dfg.de (in German). Retrieved 2023-03-02.{{cite web}}: CS1 maint: unrecognized language (link)
  11. "L'Istituto - Accademici - Marino Zerial". www.istitutoveneto.it (in italiano). Retrieved 2023-03-02.
  12. "Marino Zerial". American Academy of Arts & Sciences. Retrieved 2023-03-02.

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