William Henry Gerwick
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William Henry Gerwick | |
|---|---|
| Born | October 10, 1954 Berkeley, California, U.S. |
| Nationality | American |
| Alma mater | University of California, Davis (B.S.); Scripps Institution of Oceanography, UC San Diego (Ph.D.) |
| Known for | Marine natural products; Bioactive cyanobacterial metabolites |
| Scientific career | |
| Fields | Natural products chemistry; Marine pharmacognosy |
| Institutions | University of California, San Diego |
| Website | https://wgerwick.scrippsprofiles.ucsd.edu/ |
William Henry Gerwick (born October 10, 1954) is an American natural products chemist whose research focuses on bioactive secondary metabolites from marine algae and cyanobacteria.[1] He is a Distinguished Professor at the University of California, San Diego, with joint appointments at the Scripps Institution of Oceanography and the Skaggs School of Pharmacy and Pharmaceutical Sciences.
Gerwick is known for contributions to marine natural products chemistry, including the discovery and structural characterization of biologically active compounds from marine cyanobacteria, and for work on biosynthetic pathways and computational approaches to natural product identification.[2]
Early life and education
Gerwick was born in Berkeley, California, and grew up in Oakland. He earned a Bachelor of Science in Biochemistry from the University of California, Davis, in 1976. He completed a Ph.D. in Oceanography at the Scripps Institution of Oceanography, University of California, San Diego, in 1981, where his dissertation examined natural products chemistry within brown algae of the family Dictyotaceae.
Career
Gerwick began his academic career at the University of Puerto Rico in 1982 before joining Oregon State University in 1984, where he became a full professor in 1992.[3] In 2005, he joined the University of California, San Diego, with joint appointments at the Scripps Institution of Oceanography and the Skaggs School of Pharmacy and Pharmaceutical Sciences.[4] He was named Distinguished Professor in 2011.
From 2015 to 2020, he served as director of the Center for Marine Biotechnology and Biomedicine at Scripps Institution of Oceanography.[4]
Gerwick has also served on national scientific advisory and review panels, including selection to a National Institutes of Health committee.[5]
Research
Gerwick’s research centers on the discovery, structural elucidation, and biosynthesis of natural products from marine cyanobacteria and algae. His work has been highlighted in international science coverage addressing the importance of marine ecosystems for future drug discovery.[6]
His laboratory has reported metabolites with anticancer, antiviral, and anti-inflammatory activities, and has contributed to understanding their biosynthetic origins through genomic and biochemical studies.[7]
Related work from his group has been covered by science news outlets for identifying natural products with potential to disrupt viral spread.[8][9]
Gerwick has also contributed to computational approaches for natural product annotation and structure prediction, collaborating with computer scientists to apply machine-learning methods to spectroscopic data.[10]
Honors and awards
Gerwick has received multiple honors for his scientific contributions, including election as a Fellow of the American Society of Pharmacognosy and the American Association for the Advancement of Science, as well as the Norman R. Farnsworth Research Achievement Award from the American Society of Pharmacognosy.
He has been invited to deliver named lectures, including the Walker Lecture at the University of Mississippi.[11]
Personal life
Gerwick is married to Lena Gerwick, a cellular and molecular biologist. The couple has coauthored scientific publications.
References
- ↑ Cousins, Sophie (2026). "Sunken treasures: drug discovery in the ocean". The Lancet. 407 (10523): 16–17. doi:10.1016/S0140-6736(25)02586-3. ISSN 0140-6736.
- ↑ Linington, Roger G.; Keller, Lena; Choi, Hyukjae; Bertin, Matthew J. (March 25, 2022). "Special Issue in Honor of Professor William Gerwick". Journal of Natural Products. 85 (3).
{{cite journal}}: CS1 maint: date and year (link) - ↑ "Natural products research expands with new discovery". Oregon State University News.
- ↑ 4.0 4.1 "Scripps Professor Receives Research Achievement Award". UC San Diego News.
- ↑ "OSU prof selected for national group". Oregon State University News.
- ↑ "Call to protect marine ecosystems for future drug discovery". The Hindu BusinessLine.
- ↑ Moore, Bradley S.; Gerwick, William H. (2010). "Biologically active metabolites from marine cyanobacteria". Current Opinion in Biotechnology. 21: 1–8.
- ↑ "Researchers identify natural products with potential to disrupt viral spread". News-Medical. 5 January 2021.
- ↑ "Researchers identify natural products with potential to disrupt viral spread". EurekAlert!.
- ↑ "A convolutional neural network–based approach for rapid annotation of molecularly diverse natural products". Journal of the American Chemical Society. 2020. doi:10.1021/jacs.9b13786.
- ↑ "Walker Lecture Series: William Gerwick". University of Mississippi News.
External links
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