Tetramethyl bisphenol F

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Tetramethyl bisphenol F (TMBPF), branded as valPure V70, is a new coating intended as a safer replacement for BPA as a liner for Aluminum and Steel cans.

According to tests TMBPF does not have any effect on the endocrine system, it does not leech out of cans because unlike BPA it is fully polymerized when deposited on the metal, so there is no free chemical to leech out.[1] Tetramethyl bisphenol F was tested on rats to see if there were effects like male or female hormones. It had almost no effects like this.[2] However a different study did find effects.[3]

Polymerisation of tetramethyl bisphenol F occurs with epoxy chloropropane when heated between 40 and 70°C using an alkali as a catalyst to form the resin used as a coating.


  1. Cornwall, Warren (23 January 2020). "To replace controversial plastic additive BPA, a chemical company teams up with unlikely allies". Science | AAAS.
  2. Maffini, Maricel V.; Canatsey, Ryan D. (January 2020). "An expanded toxicological profile of tetramethyl bisphenol F (TMBPF), a precursor for a new food-contact metal packaging coating". Food and Chemical Toxicology. 135: 110889. doi:10.1016/j.fct.2019.110889.
  3. "TMBPF as BPA alternative for coating epoxies | Food Packaging Forum". www.foodpackagingforum.org.

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