Peter Valent

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Peter Valent
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Born (1962-10-09) October 9, 1962 (age 59)
Vienna, Austria
NationalityAustrian
EducationMedicine
Alma materMedical University of Vienna
Occupation
  • Hematologist
  • Stem Cell Researcher
Awards
  • Karl Landsteiner-Award
  • Wilhelm Türk Award
  • Theodor-Billroth Medal
  • Mac Forster Award

Peter Valent (October 9 1962, Vienna, Austria) is an Austrian Hematologist and Stem Cell Researcher. Since 1990 he leads a research group at the Medical University of Vienna.

Life and education

Valent studied Medicine at the Medical University of Vienna and graduated in 1987. He is a specialist in Internal Medicine and Hematology and was promoted to Assistant Professor for Experimental Hematology in 1992 and Associate Professor for Internal Medicine in 1995. Valent visited several Universities in Germany as Guest Scientist, including the Institute of Pathology of the University of Tübingen, the University of Schleswig-Holstein (Campus Lübeck) and the LMU Munich.[1]

Scientific contributions

Contributions to Mast Cell Research and the Classification of Mastocytosis

Between 1989 und 1999 Valent examined the phenotype and growth characteristics of human mast cells. He found that mast cells form a unique lineage in the hematopoietic cell system. In subsequent studies, neoplastic mast cells were characterized.[2] The resulting data contributed essentially to the development of diagnostic criteria and the WHO classification of mastocytosis. In 2000, Valent organized a Working Conference on Mastocytosis to implement this classification together with an international consensus group.[3] Since 2002 Valent coordinates the European Competence Network on Mastocytosis that expanded rapidly and provides a useful basis for the development and conduct of studies and activities in the field of mastocytosis[4]. In the forthcoming years, the diagnostic WHO criteria of mastocytosis were validated, adjusted and extended.[5] To discuss these developments, Valent and his team organized additional conferences in Vienna, including a Working Conference on Standards and Standardization of Diagnostic Criteria and Therapies in Mastocytosis[6]. and one on the Global Classification of Mast Cell Disorders and Mast Cell Activation Syndromes (2010)[7].

Additional scientific contributions

One additional focus in Valent´s research is the neoplastic stem cell, also termed cancer stem cell in the context of cancer and leukemic stem cell in leukemia contexts. Valent investigates the phenotype of these cells in various hematologic neoplasms and develops concepts predicting the step-wise development of these cells from normal stem cells. The major aim in his research is to identify molecular targets in these cells and to develop more effective (curative) therapies by eliminating these cells in various blood cell disorders, including Acute Myeloid Leukemia, Chronic Myeloid Leukemia[8], Systemic Mastocytosis[9] and Myelodysplastic Syndromes[10]. These studies are primarily conducted in the Ludwig Boltzmann Institute for Hematology and Oncology at the Medical University of Vienna.[11]

Publications

Valent is member in a number of scientific societies and produced over 800 publications in his career, including more than 500 original articles, over 200 review articles and several chapters in world-leading text books in Hematology and Pathology.[12] In 2001, 2008 und 2016, he also served as author in the WHO Book chapter on mastocytosis.[13] Overall, his publications are cited over 30.000 times and his h-Index (based on Web of Science, March 2020) is 94.[14]

Awards

Valent received several national and international awards, including the Karl Landsteiner-Award of the Austrian Society for Allergy and Immunology, the Paracelsus Award of the Austrian Society for Internal Medicine, the Wilhelm Türk Award of the Austrian Society for Hematology and Oncology, the Theodor-Billroth Medal of the Austrian Medical Association, the Mac Forster Award of the European Society for Clinical Investigation and the Middle European Award for Interdisciplinary Cancer Research.[15]

References

  1. Peter Valent - Scientific CV, retrieved 13. March 2020 in Meduniwien.ac.at
  2. The riddle of the mast cell: kit(CD117)-ligand as the missing link?, retrieved 16. April 2020 in Europepmc.org
  3. Classification and response criteria in mastocytosis: is there a need to revise?, retrieved 16. April 2020 in Expert Review of Hematology, Page 247
  4. European Competence Network on Mastocytosis (ECNM): 10-year jubilee, update, and future perspectives, retrieved 15. April 2020 in Ncbi.nlm.nih.gov
  5. Peter VALENT, MD, retrieved 8. April 2020 in Phd-mcca.at
  6. Standards and standardization in mastocytosis: Consensus Statements on Diagnostics, Treatment Recommendations and Response Criteria, retrieved 8. April 2020 in Onlinelibrary.wiley.com
  7. Definitions, Criteria and Global Classification of Mast Cell Disorders with Special Reference to Mast Cell Activation Syndromes: A Consensus Proposal, retrieved 8. April 2020 in Karger.com
  8. Immunotherapy-Based Targeting and Elimination of Leukemic Stem Cells in AML and CML, retrieved 15. April 2020 in Ncbi.nlm.nih.gov
  9. How I treat patients with advanced systemic mastocytosis, retrieved 15. April 2020 in Ncbi.nlm.nih.gov
  10. Proposed minimal diagnostic criteria for myelodysplastic syndromes (MDS) and potential pre-MDS conditions, retrieved 15. April 2020 in Ncbi.nlm.nih.gov
  11. Professor Peter Valent, MD, retrieved 8. April 2020 in Cml-foundation.org
  12. Peter Valent Publication list, retrieved 15. April 2020 in Publons.com
  13. Mastocytosis: 2016 updated WHO classification and novel emerging treatment concepts, republished on 28. December 2016 in Ncbi.nlm.nih.gov
  14. Peter Valent, retrieved 8. April 2020 in Publons.com
  15. Univ.-Prof. Dr. Peter Valent, retrieved 8. April 2020 in Meduniwien.ac.at

External links

This article "Peter Valent" is from Wikipedia. The list of its authors can be seen in its historical. Articles taken from Draft Namespace on Wikipedia could be accessed on Wikipedia's Draft Namespace.