Nicola Sarandria

Nicola Sarandria
Born	Padua, Italy
Other names	C. Wain
Education	Humanitas University (MD)North Wales Management School (MBA)Harvard Medical School (Postgraduate Diploma)PhD (Switzerland)
Occupation	Physician, researcher, entrepreneur, author
Known for	Immuno-oncology research, healthcare management, aging studies, fantasy and experimental literature
Works	A Literature Review in Immuno-Oncology: Pathophysiological and Clinical Features of Colorectal Cancer and the Role of the Doctor-Patient Interaction Private Medical Departments after COVID-19 Neutrophils in Rectal Cancer: The Sarandria Score The Sarandria Theory Debunking Aging Corde vocali Goemul e altri racconti

Nicola Sarandria is an Italian physician, researcher, entrepreneur and author active in both scientific and literary fields. His work includes publications in immuno-oncology, healthcare management, and aging, as well as narrative works associated with dark fantasy, fantasy fiction, and experimental writing. In the literary field, he has also published under the pseudonym C. Wain.

Sarandria is the author and co-author of scientific works such as A Literature Review in Immuno-Oncology: Pathophysiological and Clinical Features of Colorectal Cancer and the Role of the Doctor-Patient Interaction, Private Medical Departments after COVID-19 and Neutrophils in Rectal Cancer: The Sarandria Score. His works also include The Sarandria Theory, Debunking Aging, Corde vocali and Goemul e altri racconti.

Other short stories, flash-fiction texts, and experimental works attributed to the author include Rusalka, To love you under the rain and A young medical doctor’s thoughts on life: Fairness in the Scientific World and living a life of truth.

Life and education

Nicola Sarandria was born in Padua, Italy. He graduated in Medicine and Surgery and subsequently completed academic and professional programs abroad, including experiences in the United Kingdom, Switzerland, and the United States. He graduated with 110 cum laude from Humanitas University in Milan. He went on by completing his MBA in Healthcare Management from North Wales Management School and a PhD in Switzerland. He also holds a post-graduate diploma in cancer genomics and immuno-oncology from Harvard Medical School.

His professional path has developed around medicine, clinical research, immuno-oncology, and scientific publishing. During his university years, he also became interested in experimental music, composing under the pseudonym Vi-S0. This creative activity stands alongside his scientific and literary output.

He travelled extensively and lived in several countries. From Italy and across Europe to USA, UK, Asia, Russia and Africa.

On his maternal side Sarandria comes from the ancient branches of the Princes of Noia Pignatelli and Folch de Cardona family (South Italian branches - Spanish - Princes of the Sacred Roman Empire).

Career

Sarandria’s career has developed along two main lines: medical research and writing. In the scientific field, he has mainly worked on colorectal carcinoma, rectal cancer, immuno-oncology, and the role of tumor-associated neutrophils. In the literary field, he has published works of fantasy and dark fantasy fiction, combining medical research with an independent narrative production.

Sarandria’s scientific output is mainly connected to immuno-oncology and the study of colorectal carcinoma. In 2022 he published A Literature Review in Immuno-Oncology: Pathophysiological and Clinical Features of Colorectal Cancer and the Role of the Doctor-Patient Interaction in the Journal of Cancer Therapy. The article analyzes the pathophysiological and clinical aspects of colorectal carcinoma and also addresses the role of doctor-patient interaction in the oncological context.

In the same period, Sarandria co-authored Private Medical Departments after COVID-19: A Review and Essay Regarding the Need for Improvement of Medical Facilities and the Need of Proper Healthcare Management, published in the American Journal of Industrial and Business Management. The essay, written with Domenico Sarandria and Marcella Cardone, focuses on healthcare management and the need to improve the organization of medical facilities in the period following the COVID-19 pandemic.

Another relevant contribution is Neutrophils in Rectal Cancer: The Sarandria Score, published in the volume New Horizons in Medicine and Medical Research Vol. 7. The work presents the so-called Sarandria Score, described as a prognostic and predictive clinical score related to rectal cancer and the role of neutrophils.

In 2025 he published Debunking Aging, a medical essay published by Santelli Editore in the InMedicine series. The text is dedicated to the biological and medical aspects of aging.

Also in 2025, he launched the OR1 - Olimpia Research One project, born from Nicola Sarandria’s determination and commitment to contributing to research on colorectal carcinoma, one of the most common malignant tumors in the world, with the aim of supporting the scientific community and, above all, patients. The project developed through more than one year of research and development. The in-depth analysis conducted within the project led to new discoveries and to the formulation of The Sarandria Theory, which led to an international conference presentation, two scientific articles, and a scientific book dedicated to the study results published by Santelli Editore.

Dr Nicola Sarandria is an entrepreneur and was involved in several projects and ventures, including being a part of a fast-growing private company valued at over 40 M dollars. He has extensive skills as a high-level executive in the med-tech world.

As of 2026 he serves as Healthcare Director for Olimpia Medical Center while being member of the board of directors and Scientific Director of Planet Healthcare. He is also involved in projects in South Korea.

Literary career

Alongside his medical and scientific work, Sarandria has developed a literary output focused mainly on fantasy, dark fantasy, grimdark, and speculative fiction. Under the pseudonym C. Wain, he published A Prayer for the Necromancer, the first volume in The Shinigami Tomes series. The book got awarded the 5 Stars Seal from Readers’ Favorite, became part of the Amazon Bestseller list and was featured in the literary magazine “Kirkus Reviews”. A manga adaptation is set to be released in 2026 in collaboration with the Moroccan manga artist Soufiane Rezzak.

The trilogy also includes Dark Light and Bakemono, later collected in The Shinigami Tomes - Gold Edition: The Complete Trilogy, a work that links the pseudonym C. Wain to the name of Dr. Nicola Sarandria.

Sarandria’s fantasy fiction is characterized by dark atmospheres, supernatural elements, fantastic creatures, and a narrative tone close to grimdark. A Prayer for the Necromancer presents a world populated by ghouls, orcs, elves, goblins, and hybrid figures, introducing characters such as Kaze, described in online literary materials as the first “demighoul.”

In “Rusalka” he was aided in the development of the story by his writer friend, Bram Stoker award winner and co-author with George RR Martin of the story “Warship”, George Guthridge.

In 2023 Sarandria published Corde vocali, issued by Rossini Editore. The book appears in the catalogs of Italian bookstores such as Hoepli, Feltrinelli, IBS, and Libraccio.

Among his most recent works is Goemul e altri racconti, published by Edizioni Clandestine and distributed by Mondadori Store, Librerie.coop, and other retailers. The volume is presented as a collection of stories with speculative and dystopian elements.

Dr Sarandria also wrote and served as author for US Army associated magazines such as “Stars and Stripes” and for NATO-UN-Peacekeeping and anti-terrorism associated magazine of COESPU.

Works

Medical essays and scientific publications

• The Sarandria Theory

The Sarandria Theory was published by Santelli Editore in 2026. The book examines the role of Arginase-1, tumor-associated neutrophils, and perineural invasion in rectal cancer.

• Debunking Aging

Debunking Aging was published by Santelli Editore in 2025 in the InMedicine series. The essay is dedicated to the biological and medical aspects of aging.

• A Literature Review in Immuno-Oncology

A Literature Review in Immuno-Oncology: Pathophysiological and Clinical Features of Colorectal Cancer and the Role of the Doctor-Patient Interaction was published in 2022 in the Journal of Cancer Therapy.

• Private Medical Departments after COVID-19

Private Medical Departments after COVID-19 was published in 2022 in the American Journal of Industrial and Business Management and was written by Nicola Sarandria, Domenico Sarandria, and Marcella Cardone.

• Neutrophils in Rectal Cancer: The Sarandria Score

Neutrophils in Rectal Cancer: The Sarandria Score was published in the volume New Horizons in Medicine and Medical Research Vol. 7 in 2022.

Literary works

• A Prayer for the Necromancer

A Prayer for the Necromancer was published under the pseudonym C. Wain and is the first volume in the dark fantasy series The Shinigami Tomes.

• Dark Light

Dark Light is part of The Shinigami Tomes trilogy and is included in The Shinigami Tomes - Gold Edition.

• Bakemono

Bakemono is part of The Shinigami Tomes trilogy and is included in The Shinigami Tomes - Gold Edition.

• The Shinigami Tomes - Gold Edition

The Shinigami Tomes - Gold Edition: The Complete Trilogy collects A Prayer for the Necromancer, Dark Light, and Bakemono.

• Corde vocali

Corde vocali was published by Rossini Editore in 2023.

• Goemul e altri racconti

Goemul e altri racconti was published by Edizioni Clandestine and is distributed by Italian retailers such as Mondadori Store and Librerie.coop.

Musical works

Misunderstood Beats experimental music Album - 2018 (Using pseudonym Vi-S0)

Awards and recognition

Sarandria’s literary work as C. Wain has received attention from Kirkus Reviews, which reviewed A Prayer for the Necromancer, highlighting its dark fantasy atmosphere, visual imagery, and construction of a narrative world populated by fantastic creatures and original characters.

According to the editorial biography published by Santelli Editore, The Shinigami Tomes first volume, A Prayer for the Necromancer, received the 5-stars seal recognition from Readers’ Favorite.

The Sarandria Theory, a medical concept developed by Dr. Nicola Sarandria. It explores how certain immune cells behave in rectal cancer. It focuses on how these cells may cause the tumor to grow and spread.The theory is based on a 2025 research study (the OR1 study) that looked closely at tumor tissue. It focuses on three key parts: 1. Tumor-Associated Neutrophils (TANs) 2. Arginase-1 (ARG1). 3. Perineural Invasion (PNI).

Private life

In the family context, the figure of Giuseppe Carmelo Cardone, “La Valletta di Malta” international award winner poet and author, is also mentioned. Works attributed to him include Novelle Ricreative, Terreno Nero, and Il volto di tutto specchiato, published by Ursini Editore in 1991.

His maternal grandmother, Prof Olimpia Bertalia, was a theologist focused on the studies of Fray Louis de Leon.

His mother is the CEO and president of a private healthcare company and his father is the chief of cardiology and vascular pathology department in Italy.

He is Christian Catholic.

He is a member of the International High IQ Society, a member of Sigma XI society and a lifetime fellow at the International Society for Development and Sustainability. He is also a member of the American Academy of Anti-aging Medicine and the Society for Immunotherapy of Cancer (SITC).

Media presence

Sarandria’s public presence is connected to both his scientific activity and his literary output. His scientific works are present on platforms and archives such as ResearchGate, SCIRP, HAL, and Semantic Scholar and PubMed.

His literary and essay works are present in the catalogs of publishers and online bookstores such as Santelli Editore, Hoepli, IBS, Feltrinelli, Mondadori Store, and Librerie.coop.

His books are also available on Amazon, Feltrinelli, Mondadori and at his Goodreads author’s profile. Some of the papers he co-authored are also available on Pubmed.

External links

• Nicola Sarandria’s ResearchGate profile
• Nicola Sarandria’s author page at Santelli Editore
• The publications indexed on SCIRP
• The HAL record for Neutrophils in Rectal Cancer: The Sarandria Score
• The page for Corde vocali
• The record for Debunking Aging
• the page for The Sarandria Theory
• The record for Goemul e altri racconti