Niamh O'Hara

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Niamh O'Hara
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NationalityAmerican
Alma materNew York University
Occupation
  • Evolutionary biologist
  • CEO

Niamh O'Hara is an evolutionary biologist and the CEO and cofounder of Biotia, a health tech company that leverages sequencing-based technology and AI software to identify microorganisms and antimicrobial resistance.

Education and early career

O’Hara attended New York University, where she received her Bachelor of Arts in biological sciences in 2005. In 2014, she received her Ph.D. in evolutionary ecology and genomics at Stony Brook University. Next, in 2015, she completed a postdoctoral fellowship in bioinformatics at Fordham University. In 2018, O’Hara completed a postdoctoral fellowship in metagenomics and business from Cornell Tech.

O’Hara co-founded Biotia in 2016, together with Dr. Chris Mason from Weill Cornell.<ref>https://tech.cornell.edu/built/biotia/<ref><ref>https://councils.forbes.com/profile/Niamh-O%E2%80%99Hara-CEO-Cofounder-Biotia/887c4627-cbee-4aca-be72-2388d566de99<ref><ref>https://www.researchgate.net/profile/Niamh-Ohara-2<ref><ref>https://www.tedmed.com/talks/show?id=798844<ref><ref>https://www.biotia.io/team-member/niamh-ohara<ref>

Biotia and GeoSeeq Foundation

During her postdoctoral fellowship at Cornell Tech, O’Hara launched a health-tech startup, Biotia, to develop novel technology to diagnose and control infectious diseases and drug resistance. Biotia is located in Brooklyn, NY.<ref>https://www.biotia.io/<ref><ref>https://tech.cornell.edu/built/biotia/<ref><ref>https://www.researchgate.net/profile/Niamh-Ohara-2<ref><ref>https://www.biotia.io/team-member/niamh-ohara<ref>

Amid the COVID-19 pandemic, she brokered a partnership with Twist Bioscience and received FDA emergency-use authorization for a Next-Generation Sequencing assay to determine genetic variants for SARS-CoV2.<ref>https://investors.twistbioscience.com/news-releases/news-release-details/twist-bioscience-and-biotia-receive-us-fda-emergency-use<ref>

In 2022, O’Hara raised an $8M Series A financing round for Biotia, led by OCA Ventures.<ref>https://www.genomeweb.com/sequencing/biotia-raises-8m-series-financing<ref>

While at Biotia, O’Hara cofounded the GeoSeeq Foundation, a nonprofit supporting pathogen biosurveillance efforts by researchers and public health officials in low- and middle-income countries. <ref>https://www.geoseeq.com/<ref>

United Nations

On February 7, 2023, O’Hara briefed the United Nations General Assembly in a panel on the “Challenges and Opportunities in Creating an Early Warning System for Global Pandemics.”<ref>https://www.un.org/pga/77/2023/02/09/un-general-assembly-hears-calls-for-pathogen-surveillance-and-early-warning-platform/<ref>

She appeared on behalf of SUNY Downstate Health Sciences University and Biotia, alongside presenting scientists from The Rockefeller Foundation, Oswaldo Cruz Foundation, and Institut Pasteur, and City University of New York.<ref>https://arxiv.org/ftp/arxiv/papers/2302/2302.00863.pdf<ref>

Research

O'Hara has published peer-reviewed articles in the fields of metagenomics<ref>https://www.cell.com/cell/pdf/S0092-8674(21)00585-7.pdf<ref><ref>https://scholar.google.com/citations?view_op=view_citation&hl=en&user=XjPckj0AAAAJ&citation_for_view=XjPckj0AAAAJ:u-x6o8ySG0sC<ref><ref>https://scholar.google.com/citations?view_op=view_citation&hl=en&user=XjPckj0AAAAJ&citation_for_view=XjPckj0AAAAJ:8k81kl-MbHgC<ref><ref>https://academic.oup.com/ofid/article/9/Supplement_2/ofac492.400/6902236<ref><ref>https://academic.oup.com/ofid/article/9/Supplement_2/ofac492.400/6902236<ref><ref>https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6934070/<ref>, genomics<ref>https://academic.oup.com/ofid/article/10/Supplement_2/ofad500.2445/7446768<ref>, evolutionary biology<ref>https://scholar.google.com/citations?view_op=view_citation&hl=en&user=XjPckj0AAAAJ&citation_for_view=XjPckj0AAAAJ:d1gkVwhDpl0C<ref> and ecology.<ref>https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0013598<ref>

As a result of the COVID-19 pandemic, O’Hara conducted research to better understand the SARS-CoV-2 virus and facilitate pathways toward tracking and treatment.<ref>https://www.nature.com/articles/s41467-021-21361-7<ref><ref>https://www.sciencedirect.com/science/article/pii/S1201971221005865<ref><ref>https://journals.asm.org/doi/abs/10.1128/msystems.00771-20<ref><ref>https://www.biorxiv.org/content/10.1101/420737v3.abstract<ref><ref>https://d1wqtxts1xzle7.cloudfront.net/98071736/e00771-20.full-libre.pdf?1675213988=&response-content-disposition=inline%3B+filename%3DEnd_to_End_Protocol_for_the_Detection_of.pdf&Expires=1703207474&Signature=fLChKdKCOWFVOKesjnGREiOpgkS0qkphIgA3x8tDmD6VLrcan-1G85jmVunLb9Vd0A7UwFY4Hg6K7~R07grI1uQ6uhRa97CjjIBvGVAwZQ1xdyk8cTRYHGMXEf2dkNVEJwt5Rc9cL4p1f9Qhaah1SMDYWa06vdMQokAqTvw4SClhOAVe9-kZ0bVHN5r1uHXjR~PJqnADT8rbBoq1YAtuNU35eo2d4D4BI3QsKmBuNjtZKaSaCER6l9HoY0L2CWotNGUrw2y~0l8z9JOo-eilHIPH-39oF42h21h-AHXL6MR0jvUPt5kd729W3JjTLgRYHFMYdjgP01SNbnlraphjVw__&Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA<ref><ref>https://www.mdpi.com/2073-4425/14/1/85<ref><ref>https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8690726/<ref><ref>https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8690673/<ref><ref>https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8644938/<ref><ref>https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7777289/<ref><ref>https://pesquisa.bvsalud.org/global-literature-on-novel-coronavirus-2019-ncov/resource/pt/ppzbmed-10.1101.2020.08.16.20172668<ref> This included specific research on vaccine development<ref>https://www.sciencedirect.com/science/article/pii/S1201971221005865<ref>, variant discovery<ref>https://scholar.google.com/citations?view_op=view_citation&hl=en&user=XjPckj0AAAAJ&citation_for_view=XjPckj0AAAAJ:8k81kl-MbHgC<ref>, and detection methodology.<ref>https://journals.asm.org/doi/abs/10.1128/msystems.00771-20<ref>

O'Hara has also conducted research on the effects of climate and temperature change on specific biological ecosystems.<ref>https://academic.oup.com/evolut/article-abstract/70/1/241/6852170<ref><ref>https://bioone.org/journals/madro%C3%83%C2%B1o/volume-63/issue-3/0024-9637-63.3.249/Factors-Affecting-the-Disease-Severity-of-Alternaria-Blackspot-In-Natural/10.3120/0024-9637-63.3.249.short<ref><ref>https://bioone.org/journals/madro%C3%83%C2%B1o/volume-63/issue-3/0024-9637-63.3.249/Factors-Affecting-the-Disease-Severity-of-Alternaria-Blackspot-In-Natural/10.3120/0024-9637-63.3.249.short<ref><ref>https://bmcecolevol.biomedcentral.com/articles/10.1186/s12862-021-01789-7<ref><ref>https://www.proquest.com/openview/2529fd4da67817995f43550c505c93fa/1?pq-origsite=gscholar&cbl=18750<ref> This included an analysis on the impact of the Mt. St. Helens volcanic event.<ref>https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0013598<ref>

Her research includes evaluating ways to protect astronauts and future space travelers from potential biological threats<ref>https://journals.asm.org/doi/abs/10.1128/mra.00923-20<ref><ref>https://journals.asm.org/doi/abs/10.1128/MRA.00570-20<ref> and understanding the effects of space on evolutionary processes.<ref>https://journals.asm.org/doi/abs/10.1128/MRA.00751-21<ref><ref>https://journals.asm.org/doi/abs/10.1128/mra.00214-21<ref><ref>https://journals.asm.org/doi/abs/10.1128/mra.01398-20<ref><ref>https://www.frontiersin.org/articles/10.3389/fmicb.2021.608478/full<ref><ref>https://journals.asm.org/doi/full/10.1128/mra.00701-20<ref><ref>https://journals.asm.org/doi/full/10.1128/mra.00817-20<ref><ref>https://journals.asm.org/doi/full/10.1128/mra.00942-20<ref><ref>https://www.researchgate.net/profile/Fathi-Karouia/publication/344373686_Draft_Genome_Sequences_of_Lactobacillales_Isolated_from_the_International_Space_Station/links/5f6d629f458515b7cf4c5219/Draft-Genome-Sequences-of-Lactobacillales-Isolated-from-the-International-Space-Station.pdf<ref>

O’Hara is credited as an inventor on US Patent No. US20190318807A1, which demonstrates systems and methods for ultra-fast identification and abundance estimates of microorganisms using a kmer-depth based approach and privacy-preserving protocols.<ref>https://patents.google.com/patent/US20190318807A1/en<ref> She is also the sole inventor listed on US Patent US11205500B2, described as systems and methods for characterization of viability and infection risk of microbes in the environment.<ref>https://patents.google.com/patent/US11205500B2/en<ref>

She has also conducted research to better understand and treat urinary tract infections<ref>https://academic.oup.com/ofid/article/9/Supplement_2/ofac492.400/6902236<ref><ref>https://academic.oup.com/ofid/article/10/Supplement_2/ofad500.2445/7446768<ref> and skin diseases<ref>https://onlinelibrary.wiley.com/doi/abs/10.1002/9781119593058.ch13<ref> while focusing on improving privacy measures<ref>https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6934070/<ref> and cleanliness standards for patients.<ref>https://academic.oup.com/ofid/article/5/suppl_1/S347/5207860<ref>

Awards and Honors

O’Hara was named a TedMed Hive Innovator of 2020.<ref>https://www.tedmed.com/event/the-hive<ref>

References

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