Kaela Singleton

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Kaela S. Singleton, PhD
Born
Fort Hood, Texas U.S.
NationalityAmerican
Alma mater
  • Agnes Scott College
  • Georgetown University
Scientific career
Fieldsneuroscience
Websitewww.kaelasingleton.com

Kaela Singleton is a queer Black and Samoan-American developmental neurobiologist whose research focuses on combining different biological approaches to study normal and abnormal neuron and nervous system development. Singleton is a postdoctoral fellow at Emory University and an adjunct professor at the Agnes Scott College biology department.[1] She is a cofounder of the organization Black in Neuro[1] and has been recognized by many different journals as a promising scientist to watch now and in the near future.

Education

Singleton received a Bachelor of Sciences in neuroscience & classical history and culture at Agnes Scott College in 2014. She then earned a PhD within the interdisciplinary program in neuroscience at Georgetown University in 2020. After earning her doctoral degree, Singleton returned to Agnes Scott College as an adjunct professor within the biology department until 2022. Intro bio, foundations of neuro, and diseases of the nervous system.

Since receiving her doctoral degree, Singleton is currently conducting research as a postdoctoral trainee at Emory University.[2][3]

Research

Kaela Singleton is interested in the general processes of growth and development and the parallels that can be drawn between neurological and character/personal development. Much of her motivations as a scientists stem from wanting to explore the connection of the biological growth processes to an individual's growth as a scientist or mentor.[3]

During graduate school at Georgetown University, Singleton conducted research within the lab of Elena Silva studying brain and neuron development.[4] Specifically, Singleton researched the functionality and regulation of sox genes, specifically sox11, which is transcription factor. Singleton used Xenopus as a model organism to study the various functions of sox11 within neural development.[5]

Singleton is currently conducting postdoctoral research within the Faundez Lab at Emory University mentored by Victor Faundez. Singleton's research is on the different cellular and genetic causes of Menkes disease. She is investigating how, lower levels of copper impacts the proper migration of mitochondria cells to the synapse in disease models.[6]

Singleton is projected to start her own research lab in 2024 where she will continue to investigate both neurotypical and pathological mechanisms of neuron development.

Select publications

  • Singleton, Kaela S.; Murray, De-Shaine R. K.; Dukes, Angeline J.; Richardson, Lietsel N. S. (2021-11-03). A year in review: Are diversity, equity, and inclusion initiatives fixing systemic barriers?[7]
  • Wynne, M. E., Lane, A. R., Singleton, K. S., Zlatic, S. A., Gokhale, A., Werner, E., Duong, D., Kwong, J. Q., Crocker, A. J., & Faundez, V.. (2021). Heterogeneous Expression of Nuclear Encoded Mitochondrial Genes Distinguishes Inhibitory and Excitatory Neurons.[8]
  • Singleton, Kaela S.; Tesfaye, Rackeb; Dominguez, Elena N.; Dukes, Angeline J. (2021-02). An open letter to past, current and future mentors of Black neuroscientists.[9]
  • Lee, Chelsea E.; Singleton, Kaela S.; Wallin, Melissa; Faundez, Victor (2020-05-22). Rare Genetic Diseases: Nature's Experiments on Human Development.[10]
  • S., Singleton, Kaela (2020). Characterization of SOX11 Partner Proteins and Interaction Domains in Xenopus Neurogenesis[11]
  • Singleton, Kaela S.; Faundez, Victor (2021-06-03). Robustness and innovation along the endocytic route: Lessons from darkness.[12]

Recent Awards and Recognition

Year Award Title Affiliation Sources
2022 30 Under 30 in Science Forbes Magazine [13]
2021 Women to Watch Neuro Central [6]
2020 Outstanding Young Alumnae Agnes Scotts College [14]
2020 1000 Inspiring Black Scientists Cell Mentor [15]
2020 Highlight as LGBTQ+ Scientist Nature Magazine [16]

Fellowships and Funding

Year Award Title Affiliation Sources
2021-2024 Burroughs Wellcome Fund Postdoctoral Enrichment Program [1]
2018-2024 Blueprint Diversity Specialized Predoctoral to Postdoctoral Advancement in Neuroscience (D-SPAN) Award National Institute of Health (NIH) [14]
2012-2014 Enhancing Undergraduates in Neuroscience Research Fellowship (ENDURE) NINDS [17]

Outreach

Kaela Singleton's outreach focuses around increasing the visibility of black and/or queer female neuroscientists. Additionally Singleton has published articles[9][18] and participated in many panels and workshops that address and promote diversity, equity, and inclusion within higher education. Singleton is the co-founder and president-elect of Black in Neuro, a global organization focused on outreach and supporting the diversity of future and current neuroscientists.[16]

Singleton has been profiled in multiple magazines and articles, such as Nature (journal)|Nature, discussing issues in science that both women and members of the LGBTQ+ community face within greater academia.[19][16][20]

References

  1. ↑ 1.0 1.1 1.2 "Black In Neuro - Member public profile". www.blackinneuro.com. Retrieved 2022-05-02.
  2. ↑ "People". Faundez Lab. Retrieved 2022-04-25.
  3. ↑ 3.0 3.1 Development, PodBean. "Tidbits of Research". tidbitsofresearch.podbean.com. Retrieved 2022-05-02.
  4. ↑ neuroscienceoutreach (2020-10-26). "Kaela Singleton, PhD". Scientist on the Subway. Retrieved 2022-05-02.
  5. ↑ Singleton, Kaela S.; Silva-Rodriguez, Pablo; Silva, Elena M. (2020-04-24). "Pairing your Sox: Identification of Sox11 partner proteins and interaction domains in the developing neural plate": 2020.04.23.057919. doi:10.1101/2020.04.23.057919v1. {{cite journal}}: Cite journal requires |journal= (help)
  6. ↑ 6.0 6.1 "Women to Watch: investigating the role of mitochondria retention in Menkes disease with Dr Kaela Singleton". Neuro Central. 2021-02-11. Retrieved 2022-05-19.
  7. ↑ Singleton, Kaela S.; Murray, De-Shaine R.K.; Dukes, Angeline J.; Richardson, Lietsel N.S. "A year in review: Are diversity, equity, and inclusion initiatives fixing systemic barriers?". Neuron. 109 (21): 3365–3367. doi:10.1016/j.neuron.2021.07.014.
  8. ↑ Wynne, Meghan E.; Lane, Alicia R.; Singleton, Kaela S.; Zlatic, Stephanie A.; Gokhale, Avanti; Werner, Erica; Duong, Duc; Kwong, Jennifer Q.; Crocker, Amanda J.; Faundez, Victor. "Heterogeneous Expression of Nuclear Encoded Mitochondrial Genes Distinguishes Inhibitory and Excitatory Neurons". eneuro. 8 (4): ENEURO.0232–21.2021. doi:10.1523/ENEURO.0232-21.2021. ISSN 2373-2822. PMC 8387155. PMID 34312306.
  9. ↑ 9.0 9.1 Singleton, Kaela S.; Tesfaye, Rackeb; Dominguez, Elena N.; Dukes, Angeline J. "An open letter to past, current and future mentors of Black neuroscientists". Nature Reviews Neuroscience. 22 (2): 71–72. doi:10.1038/s41583-020-00421-9. ISSN 1471-003X.
  10. ↑ Lee, Chelsea E.; Singleton, Kaela S.; Wallin, Melissa; Faundez, Victor. "Rare Genetic Diseases: Nature's Experiments on Human Development". iScience. 23 (5): 101123. doi:10.1016/j.isci.2020.101123. PMC 7229282. PMID 32422592.
  11. ↑ S., Singleton, Kaela (2020). "Characterization of SOX11 Partner Proteins and Interaction Domains in Xenopus Neurogenesis". {{cite journal}}: Cite journal requires |journal= (help)CS1 maint: multiple names: authors list (link)
  12. ↑ Singleton, Kaela S.; Faundez, Victor (2021-07-05). "Robustness and innovation along the endocytic route: Lessons from darkness". Journal of Cell Biology. 220 (7): e202105030. doi:10.1083/jcb.202105030. ISSN 0021-9525. PMC 8178755. PMID 34081082.
  13. ↑ "Kaela Singleton". Forbes. Retrieved 2022-05-02.
  14. ↑ 14.0 14.1 "Student Research Day 2021". Biomedical Graduate Education. 2021-09-20. Retrieved 2022-05-02.
  15. ↑ Scholars, The Community of. "1,000 inspiring Black scientists in America". crosstalk.cell.com. Retrieved 2022-05-02.
  16. ↑ 16.0 16.1 16.2 Ortega, Rodrigo Pérez (2021). "Black scientists gather to form communities and boost diversity in science". Nature Medicine. 27 (5): 756–758. doi:10.1038/s41591-021-01315-8. ISSN 1078-8956.
  17. ↑ "Get to Know our recent Guest Speaker: Dr. Kaela Singleton | Neuroscience Diversity, Equity, and Inclusion Committee". sites.gsu.edu. Retrieved 2022-05-19.
  18. ↑ Singleton, Kaela S.; Murray, De-Shaine R. K.; Dukes, Angeline J.; Richardson, Lietsel N. S. (2021-11-03). "A year in review: Are diversity, equity, and inclusion initiatives fixing systemic barriers?". Neuron. 109 (21): 3365–3367. doi:10.1016/j.neuron.2021.07.014. ISSN 0896-6273.
  19. ↑ Powell, Kendall; Terry, Ruth; Chen, Sophia (2020-10-29). "How LGBT+ scientists would like to be included and welcomed in STEM workplaces". Nature. 586 (7831): 813–816. doi:10.1038/d41586-020-02949-3. ISSN 0028-0836.
  20. ↑ "Female academics saw their own experiences with #manterrupting in this week's vice presidential debate". www.insidehighered.com. Retrieved 2022-05-23.

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