Clea Japan, Inc.
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Native name | 日本クレア株式会社 |
|---|---|
| Private (non-listed) | |
| Industry | Laboratory animal supply; Animal feed; Biomedical research support |
| Founded | February 26, 1965 |
| Headquarters | 1-2-7 Higashiyama, Meguro-ku, Tokyo 153-8533, Japan |
Key people | Takeo Sakamoto (President)[1] |
| Products | Laboratory animals; Rodent diets; Animal facility equipment; Contract research services |
| Services | Animal supply; Diets; Facility consulting; Contract services; Import/export |
Number of employees | 308 (as of April 1, 2025)[2] |
| Website | https://www.clea-japan.com/en/ |
CLEA Japan, Inc. is a Japanese company founded in 1965 and headquartered in Tokyo. The company produces laboratory animals and laboratory animal diets and provides related services for research institutions.[3]
History
CLEA Japan, Inc. was established in February 1965. According to the company history, it was founded through joint investment by the Central Institute for Experimental Medicine and Life Science (CIEM) and 18 pharmaceutical companies as an independent company to produce specific-pathogen-free (SPF) laboratory animals.[4] The company subsequently established and expanded breeding facilities in Japan, including Takatsuki (1966), Ishibe (1968), and Fuji (1970).[5]
Operations
CLEA Japan is headquartered in Meguro-ku, Tokyo, Japan.[6] Its stated business includes the production and sale of laboratory animals and laboratory animal diets; the manufacture and sale of equipment related to experimental animals; contract research services such as quarantine, testing, and model animal creation; consultation on the design and operation of animal facilities; and import and export related to laboratory animal business.[7] In addition to laboratory animals and diets, third-party sources describe the company as providing laboratory equipment and facility-related services for research environments.[8]
Products and services
Laboratory animals and diets supplied by CLEA Japan have been reported as part of experimental conditions in publicly available research protocols and institutional research pages. A Bio-protocol Exchange entry reports that C57BL/6J mice were purchased from CLEA Japan, Inc., and that the standard laboratory diet "CE-2" was used in the experiment.[9] Japan’s National Institutes of Biomedical Innovation, Health and Nutrition reports that mice were purchased from CLEA Japan and maintained on CE-2 feed supplied by the company in a body-weight profiling study.[10]
Use in academic research
Animals sourced from CLEA Japan have been reported in peer-reviewed scientific publications. A study published in the Journal of Nutritional Science reports the use of obese diabetic KK-Ay mice purchased from CLEA Japan, Inc., and the use of CE-2 as a standard laboratory diet.[11] Another study published in Heart and Vessels reports that male C57BL/6J mice purchased from CLEA Japan Inc. (Tokyo, Japan) were used in a murine ischemia–reperfusion injury model.[12] A review article in the Journal of Toxicologic Pathology describes a standardized production and monitoring system for rasH2 transgenic mice, in which cryopreserved embryos are preserved by the Central Institute for Experimental Animals and sent to production facilities including CLEA Japan as part of a global supply system.[13]
Independent recognition
An article published by The Scientist discusses standardized high-fat and control laboratory diets used in mouse research and identifies CLEA Japan as one of the suppliers providing such diets to research laboratories.[14]
Industry context
Market research reports list CLEA Japan among companies operating in the laboratory animal and animal model sector.[15][16]
Partnerships
Physiogenex, a preclinical contract research organization, lists CLEA Japan as a scientific partner and states that the two organizations have collaborated on the development of the SDT fatty rat model, with results presented at international scientific meetings.[17]
International scientific meetings
CLEA Japan maintains an academic presentation archive listing participation in domestic and international scientific meetings. The company presented research related to rasH2 transgenic mice at the AALAS 75th National Meeting in Nashville, Tennessee, in 2024.[18] Abstracts for the AALAS National Meeting are archived in official abstract collections published by the American Association for Laboratory Animal Science.[19]
Corporate information
According to the company outline, CLEA Japan reported 308 employees and capital of 170,000,000 JPY as of April 1, 2025.[20]
Conflict of interest note
The contributor of this draft has a professional affiliation with CLEA Japan, Inc. This article has been written with the intent to summarize verifiable information from independent, reliable sources in a neutral and encyclopedic manner, in accordance with Wikipedia’s conflict of interest guidelines.
References
- ↑ Clea Japan, “From Our President.” https://www.clea-japan.com/en/company/message.html
- ↑ Clea Japan, “Company Information / Outline.” https://www.clea-japan.com/en/company/outline.html
- ↑ "Company Outline". CLEA Japan.
- ↑ "Our History". CLEA Japan.
- ↑ "Our History". CLEA Japan.
- ↑ "Company Outline". CLEA Japan.
- ↑ "Company Outline". CLEA Japan.
- ↑ "Company Outline". CLEA Japan.
- ↑ "Animals and Experimental Protocol". Bio-protocol Exchange.
- ↑ "Profiling of standard mouse strains". JCRB Laboratory Animal Resource Bank.
- ↑ "Amycenone reduces excess body weight and attenuates hyperlipidaemia in KK-Ay obese diabetic mice". Journal of Nutritional Science.
- ↑ "5-Aminolevulinic acid combined with ferrous iron ameliorates myocardial ischemia/reperfusion injury". Heart and Vessels.
- ↑ "rasH2 mouse: reproducibility and stability of carcinogenicity due to a standardized production and monitoring system". Journal of Toxicologic Pathology.
- ↑ "Inside a Lab Mouse's High-Fat Diet". The Scientist.
- ↑ "Japan Animal Model Market Size and Forecast". Verified Market Research.
- ↑ "Animal Model Market - Companies". Mordor Intelligence.
- ↑ "Scientific Partners". Physiogenex.
- ↑ "AALAS 75th National Meeting". CLEA Japan.
- ↑ "Abstracts Archive". AALAS National Meeting.
- ↑ "Company Outline". CLEA Japan.
External links
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