Christopher Gregg
Christopher Gregg PhD | |
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| Born | Christopher Thornton Gregg August 27, 1975 Calgary, Canada |
| Nationality | Canadian |
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| Known for | Behavioral A.I. |
Christopher Gregg PhD (born August 27, 1975) is a Canadian researcher, futurist, and entrepreneur. He is a tenured professor in the Departments of Neurobiology & Anatomy and Human Genetics at the University of Utah School of Medicine, director of the Gregg Lab, and Chief Science Officer and co-founder of Storyline Health Inc..[1] [2] [3]
Personal life
Christopher Gregg was born August 27 1975 in Calgary, Canada. He currently lives in Salt Lake City, Utah with his wife and 2 children. [1]
Career
Gregg was an undergraduate at the University of Lethbridge where he received a B.Sc. in biochemistry before receiving his PhD from the University of Calgary in Canada in neural stem cell biology. While working with Samuel Weiss at the Hotchkiss Brain Institute he received the University of Calgary Chancellor’s Medal for recognition of his work on Stem cell|stem cells and regenerative therapies. This work led to his first biotech company; Stem Cell Therapeutics. [1]
In 2006 Gregg moved to Harvard University as a postdoc where he received a Human Frontiers Fellowship, working with Dr. Catherine Dulac in the Dulac Lab, developing RNASeq methods to distinguish the expression of paternal and maternalalleles in the brain. [4]
In 2011 Gregg joined both the University of Utah Departments of Neurobiology & Human Genetics where he founded the Gregg Lab.[2] He was awarded tenure in 2019. The Gregg Lab played an early role in the development of sequencing technologies used to study study allele-specific expression effects using RNA-seq. This work revealed genes that exhibit a maternal or paternal allele expression bias and uncovered forms of genomic imprinting and parental influence on brain gene expression - significantly shaping offspring behavior. [5]
Gregg received certificates from Cold Spring Harbor Laboratory for Integrative Statistical Analysis of Genomic Data and Programming for Biology. [1]
In 2019 Gregg co-founded Storyline Health Inc., an A.I. company using human behavior to discover and deliver biomarkers of health and disease. [3]
Awards and recognition
- In 2010 he was awarded the Eppendorf & Science Prize in Neurobiology. [6] [7]
- In 2010 his work was chosen as one of the “Top 10 Breakthroughs of the Year” by the National Institutes of Mental Health
- In 2012 he was chosen to be a New York Stem Cell Foundation Robertson Investigator. [8]
- In 2018 his work was selected by STAT News as one of the breakthroughs of the year.
Research
Gregg's research interest lies at the intersection of genomics and behavior, genetic and epigenetic mechanisms in the brain that regulate motivated behaviors. Reesarch using mouse models has shown show that gene expression directly affects behavior and that A.I. can be used to find behavioral biomarkers. [1] [9] [10]
Cancer
In 2018 Chris Gregg was diagnosed with terminal stage 4 metastatic cancer and given an estimated life expectancy of 18-24 months. In response to his diagnosis he reviewed scientific literature and became aware of a clinical trial conducted in Moffitt Cancer Center on patients with metastatic castrate-resistant prostate cancer showed outcomes that "show significant improvement over published studies and a contemporaneous population."[11] Gregg created a consortium of oncologists and researchers from Moffitt, Huntsman Cancer Institute, and others to improve cancer care pathways based upon evolutionary and adaptive therapy with an additional goal of educating cancer patients. [12][13][14][15] In 2022 Gregg revealed in a video that he had shown no evidence of disease (NED) for almost 3 years. [16]
References
- ↑ 1.0 1.1 1.2 1.3 1.4 "University of Utah School of Medicine". University of Utah School of Medicine Faculty Profile.
- ↑ 2.0 2.1 "Gregg Lab". Gregg Lab Website.
- ↑ 3.0 3.1 "Storyline Health". Storyline Health.
- ↑ Dulac, Catherine. "Dulac Lab". Dulac Lab. Harvard University.
- ↑ "TEDx Talk: Why Sex? Science Has an Answer". TEDx. Tedx.
- ↑ "2010 Eppendorf prize winners". Science.org.
- ↑ "Christopher Gregg Wins Eppendorf & Science Prize for Research on How Parents' Genes Shape Child's Brain". American Association for the Advancement of science.
- ↑ "New York Stem Cell Foundation Robertson Investigator". New York Stem Cell Foundation.
- ↑ "National Library of Medicine, bibliography". National Institute of Health (NIH).
- ↑ Gregg, Christopher (August 13, 2019). "Complex Economic Behavior Patterns Are Constructed from Finite, Genetically Controlled Modules of Behavior". Cell Reports. 38 (7): 1814–1829. doi:10.1016/j.celrep.2019.07.038. PMC 7476553. PMID 31412249. S2CID 199662477.
- ↑ Zhang J, Cunningham JJ, Brown JS, Gatenby RA (November 2017). "Integrating evolutionary dynamics into treatment of metastatic castrate-resistant prostate cancer". Nature Communications. 8 (1): 1816. Bibcode:2017NatCo...8.1816Z. doi:10.1038/s41467-017-01968-5. PMC 5703947. PMID 29180633.
- ↑ Gregg, Chris. "Cancer Patient Education". Uncharted Health.
- ↑ Gregg, Chris. "Cancer Advisory Board". Uncharted Health.
- ↑ Kim E, Brown JS, Eroglu Z, Anderson AR (February 2021). "Adaptive Therapy for Metastatic Melanoma: Predictions from Patient Calibrated Mathematical Models". Cancers. 13 (4): 823. doi:10.3390/cancers13040823. PMC 7920057. PMID 33669315.
- ↑ Gatenby RA, Silva AS, Gillies RJ, Frieden BR (June 2009). "Adaptive therapy". Cancer Research. 69 (11): 4894–4903. doi:10.1158/0008-5472.CAN-08-3658. PMC 3728826. PMID 19487300.
- ↑ Gregg, Chris. "Cancer Video". Uncharted Health.
External links
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