Amir Manbachi

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Amir Manbachi
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NationalityIran-Canada
Occupation
  • Biomedical engineer
  • scientist
  • inventor
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Academic background
Education
  • BA
  • MA
  • Ph.D.
Alma materUniversity of Toronto
Academic work
Main interests
  • Image-guided surgery
  • Medical ultrasound
  • Therapeutic ultrasound
  • Neuromodulation

Amir Manbachi is a Iranian-Canadian scientist, inventor, and entrepreneur in the field of ultrasound.[1] His research and inventions are primarily centered around spine and brain surgeries. Manbachi is an Assistant Professor of Neurosurgery at Johns Hopkins' School of Medicine.He is the director of the Johns Hopkins' HEPIUS lab.[2][3][4][5][6][7][8][9]

Background

Manbachi is Canadian of Iranian descent.[10][11]

He conducted his doctoral studies under the supervision of ultrasound connoisseur, Richard S.C. Cobbold at the University of Toronto.[12]

He studied at the University of Toronto where he graduated with a bachelor's degree in Applied Sciences (BASc) from the Engineering Science (Physics) program in 2008.In 2010, he got his master's degree, and in 2015 he got a PhD in biomedical engineering from University of Toronto.[13]

During his post-doctoral research at Harvard and MIT's Division of Health Sciences Technology, his mentor was Ali Khademhosseini.[14][15]

In 2020, and as part of a team jointly led by Nicholas Theodore at Johns Hopkins Medicine, Manbachi and his team received a $13.5M grant from the Defense Advanced Research Projects Agency (DARPA) to develop wearable and implantable ultrasound technologies for patients with spinal cord injuries.[16][17]

Career

As of December 2022, Manbachi is an Assistant Professor of neurosurgery, biomedical engineering, mechanical engineering, electrical and computer engineering, Anesthesiology, and Critical Care Medicine at Johns Hopkins University. He is a member of the Biomedical Engineering Society, the Institute of Electrical and Electronics Engineers (IEEE), and the Society of Photo-Optical Instrumentation Engineers (SPIE).He is credited with dozen patents and patent applications pertaining to medical devices for wearable and implantable ultrasound probes.[18] Manbachi studied the utility of machine learning to automatically detect and localize foreign body objects on intraoperative ultrasound images.[19] Another example of his work includes the design and fabrication of implantable ultrasound sensors to monitor brain tumor regrowth following surgeries.[20][21] Manbachi's work has been recently recognized by Baltimore Business Journal’s 40 under 40 award.[18]

Bibliography

Select publications

  • Manbachi A. and Cobbold R.S.C., 2011. Development and application of piezoelectric materials for ultrasound generation and detection. Ultrasound, 19(4), pp. 187–196.
  • Kempksi Leadingham KM, Abramson HG, Perdomo-Pantoja A, Thombre R, Liu J, Norman M, Chavez F, Morrison K, Suk I, Gordon C, Armand M and Manbachi A. "Design of a Custom Flexible Ultrasound Transducer as an Implantable Cranial Sensor for Long-Term Post-Operative Monitoring of Brain Tumor Regrowth," 2022 IEEE International Ultrasonics Symposium (IUS), 2022, pp. 1–4, doi:10.1109/IUS54386.2022.9958345
  • Routkevitch D, Hersh AM, Kempski KM, Kerensky M, Theodore N, Thakor NV, Manbachi A, "FlowMorph: Morphological Segmentation of Ultrasound-Monitored Spinal Cord Microcirculation," 2022 IEEE Biomedical Circuits and Systems Conference (BioCAS), 2022, pp. 610–614, doi:10.1109/BioCAS54905.2022.9948639

As an editor

  • Manbachi, Amir; M. Kempski Leadingham, Kelley; J. Curry, Eli (28 November 2022). The Abundant Promise of Ultrasound in Neurosurgery: A Broad Overview and Thoughts on Ethical Paths to Realizing Its Benefits. ISBN 9781510657250.

References

  1. ↑ "Amir Manbachi, Ph.D., M.Sc., Assistant Professor of Neurosurgery". Johns Hopkins Medicine.
  2. ↑ Condon, Alan. "Johns Hopkins surgeons awarded $13M+ to develop ultrasound devices for spinal cord injury". beckersspine.com.
  3. ↑ "Cross-disciplinary team will design, develop devices to better treat spinal cord injuries". Spinal Cord Injury Zone!. November 11, 2020.
  4. ↑ Kimberly Skarupski (January 29, 2021). "Habits and Hacks with Amir Manbachi, PhD".
  5. ↑ "STTR Phase I: Minimally Invasive, High-Intensity Focused Ultrasound Device for Ablation of Brain Tumors | SBIR.gov". sbir.gov.
  6. ↑ "CTV News | Canada News | Local News". ctvnews.ca.
  7. ↑ "The Story of a Student Entrepreneur: Turning PhD Research into an Investment Opportunity". January 9, 2015.
  8. ↑ "A Discovery of Talent and Drive". Biomedical Engineering – University of Toronto.
  9. ↑ "Public statement by Professors Ali Khademhosseini, Reza Moridi and Amir Manbachi, on the besiegement of Sharif University 2022" – via vimeo.com.
  10. ↑ "استاد ایرانی دانشگاه جانز هاپکینز: جامعه علمی باید از حق دفاع کند". صدای آمریکا. December 25, 2022.
  11. ↑ "Princely Persian performers". The Varsity. January 23, 2007.
  12. ↑ "Amir Manbachi, PhD - Editorial Board - Ultrasonics - Journal - Elsevier". www.journals.elsevier.com.
  13. ↑ "The path to a faculty position: Q & A with alumnus Amir Manbachi". Biomedical Engineering - University of Toronto. June 23, 2016.
  14. ↑ Miri, Amir K.; Nieto, Daniel; Iglesias, Luis; Goodarzi Hosseinabadi, Hossein; Maharjan, Sushila; Ruiz-Esparza, Guillermo U.; Khoshakhlagh, Parastoo; Manbachi, Amir; Dokmeci, Mehmet Remzi; Chen, Shaochen; Shin, Su Ryon; Zhang, Yu Shrike; Khademhosseini, Ali (July 16, 2018). "Bioprinting: Microfluidics-Enabled Multimaterial Maskless Stereolithographic Bioprinting (Adv. Mater. 27/2018)". Advanced Materials. 30 (27): 1870201. doi:10.1002/adma.201870201 – via CrossRef.
  15. ↑ https://bntl.sogang.ac.kr/bntl/Research/Documents/8.pdf
  16. ↑ "Focused Ultrasound for Spinal Cord Injury: Johns Hopkins Receives Funding for New Device". October 30, 2020.
  17. ↑ "$13.48M Awarded To Johns Hopkins Scientists To Develop Implantable Ultrasound Devices For Patients With Spinal Cord Injury". newswise.com.
  18. ↑ 18.0 18.1 https://www.bizjournals.com/baltimore/news/2022/09/19/baltimore-business-journal-40-under-40-2022.html
  19. ↑ Abramson, Haley G.; Curry, Eli J.; Mess, Griffin; Thombre, Rasika; Kempski-Leadingham, Kelley M.; Mistry, Shivang; Somanathan, Subhiksha; Roy, Laura; Abu-Bonsrah, Nancy; Coles, George; Doloff, Joshua C.; Brem, Henry; Theodore, Nicholas; Huang, Judy; Manbachi, Amir (December 8, 2022). "Automatic detection of foreign body objects in neurosurgery using a deep learning approach on intraoperative ultrasound images: From animal models to first in-human testing". Frontiers in Surgery. 9. doi:10.3389/fsurg.2022.1040066. PMC 9748097. PMID 36532130.
  20. ↑ Leadingham, Kelley M. Kempski; Abramson, Haley G.; Perdomo-Pantoja, Alexander; Thombre, Rasika; Liu, Joshua; Norman, Madison; Chavez, Francisco; Morrison, Kyle; Suk, Ian; Gordon, Chad; Armand, Mehran; Manbachi, Amir (October 7, 2022). "Design of a Custom Flexible Ultrasound Transducer as an Implantable Cranial Sensor for Long-Term Post-Operative Monitoring of Brain Tumor Regrowth". 2022 IEEE International Ultrasonics Symposium (IUS). pp. 1–4. doi:10.1109/IUS54386.2022.9958345. ISBN 978-1-6654-6657-8 – via IEEE Xplore.
  21. ↑ Hersh, Andrew M.; Bhimreddy, Meghana; Weber-Levine, Carly; Jiang, Kelly; Alomari, Safwan; Theodore, Nicholas; Manbachi, Amir; Tyler, Betty M. (October 8, 2022). "Applications of Focused Ultrasound for the Treatment of Glioblastoma: A New Frontier". Cancers. 14 (19): 4920. doi:10.3390/cancers14194920. PMC 9563027. PMID 36230843.

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